Abstract:
Diabetes mellitus is the most common endocrine disorder that impairs glucose homeostasis resulting in
severe diabetic complications including retinopathy, angiopathy, nephropathy, and causing neurological disorders
due to perturbation in utilization of glucose. The present study was designed to investigate the hypoglycemic
properties of ethanolic extract of Nardostachys jatamansi (N. jatamansi) which is widely used as a traditional
treatment for diabetes mellitus. The present study was carried out to evaluate the antidiabetic activity of
Nardostachys jatamansi ethanolic rhizome extract in alloxan induced diabetic rats for 7 days. The ethanolic extract
at high dose (1200 mg/kg) exhibited significant antihyperglycemic activity than at low dose (400 mg/kg) in diabetic
rats. The results showed that it has significant antihyperglycemic effect in experimental model of diabetes mellitus.
