Abstract:
The hypoglycemic effect of Methanolic extract Ximenia americana was evaluated in normal glucose fed and
alloxan-induced diabetic rats. Oral administration of extract (200, 400 and 600mg/kg bw) for seven days resulted in a
significant reduction in blood glucose level. The effect was compared with 0.5gm/kg (i.p) glibenclamide. Alloxan induced
hyperglycemia and glucose fed hyperglycemia rat models were used for the evaluation of anti-diabetic activity. The effect of
MEXA of normalglycemic, glucose fed hyperglycemic activity and alloxan induced hyperglycemic activity were showed in
dose dependant manner. Activity is more for 600mg/kg bw dose in comparision with 400 and 200mg/kg bw dose.
