Cost-effectiveness of cervical cancer screening and preventative cryotherapy at an HIV treatment clinic in Kenya

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dc.contributor.author Zimmermann, Marita
dc.contributor.author Vodicka, Elisabeth
dc.contributor.author Babigumira, Joseph
dc.contributor.author Okech, Timothy
dc.contributor.author Mugo, Nelly
dc.contributor.author Sakr, Samah
dc.contributor.author Garrison, Louis
dc.contributor.author Chung, Michael
dc.date.accessioned 2019-08-09T09:31:34Z
dc.date.available 2019-08-09T09:31:34Z
dc.date.issued 2017
dc.identifier.uri http://erepo.usiu.ac.ke/11732/4732
dc.description Journal article en_US
dc.description.abstract Objective: This study evaluated the potential cost-effectiveness of cervical cancer screening in HIV treatment clinics in Nairobi, Kenya.Methods: A Markov model was used to project health outcomes and costs of cervical cancer screening and cryo-therapy at an HIV clinic in Kenya using cryotherapy without screening, visual inspection with acetic acid (VIA), Papani-colaou smear (Pap), and testing for human papillomavirus (HPV ). Direct and indirect medical and non-medical costs were examined from societal and clinic perspectives.Results: Costs of cryotherapy, VIA, Pap, and HPV for women with CD4 200–500 cells/mL were $99, $196, $219, and $223 from a societal perspective and $19, $94, $124, and $113 from a clinic perspective, with 17.3, 17.1, 17.1, and 17.1 years of life expectancy, respectively. Women at higher CD4 counts (>500 cells/mL) given cryotherapy VIA, Pap, and HPV resulted in better life expectancies (19.9+ years) and lower cost (societal: $49, $99, $115, and $102; clinic: $13, $51, $71, and $56). VIA was less expensive than HPV unless HPV screening could be reduced to a single visit.Conclusions: Preventative cryotherapy was the least expensive strategy and resulted in highest projected life expec-tancy, while VIA was most cost-effective unless HPV could be reduced to a single visit.Keywords: Cervical cancer, Cost effectiveness, HIV, VIA, Cryotherapy en_US
dc.publisher BioMed central en_US
dc.subject Cost-effectiveness, cervical cancer, screening en_US
dc.title Cost-effectiveness of cervical cancer screening and preventative cryotherapy at an HIV treatment clinic in Kenya en_US
dc.type Article en_US

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