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Evaluation of ICT Filariasis Card Test Using Whole Capillary Blood: Comparison with Knott's Concentration and Counting Chamber Methods

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dc.contributor.author Njenga, S.M.
dc.contributor.author Wamae, C.N.
dc.date.accessioned 2018-05-11T09:28:15Z
dc.date.available 2018-05-11T09:28:15Z
dc.date.issued 2001
dc.identifier.uri http://erepo.usiu.ac.ke/11732/3827
dc.description Article Journal en_US
dc.description.abstract An immunochromatographic card test (ICT) that uses fingerprick whole blood instead of serum for diagnosis of bancroftian filariasis has recently been developed. The card test was validated in the field in Kenya by comparing its sensitivity to the combined sensitivity of Knott’s concentration and counting chamber methods. A total of 102 (14.6%) and 117 (16.7%) persons was found to be microfilaremic by Knott’s concentration and counting chamber methods, respectively. The geometric mean intensities (GMI) were 74.6 microfilariae (mf)/ml and 256.5 mf/ml by Knott’s concentration and counting chamber methods, respectively. All infected individuals detected by both Knott’s concentration and counting chamber methods were also antigen positive by the ICT filariasis card test (100% sensitivity). Further, of 97 parasitologically amicrofilaremic persons, 24 (24.7%) were antigen positive by the ICT. The overall prevalence of antigenemia was 37.3%. Of 100 nonendemic area control persons, none was found to be filarial antigen positive (100% specificity). The results show that the new version of the ICT filariasis card test is a simple, sensitive, specific, and rapid test that is convenient in field settings. en_US
dc.language.iso es en_US
dc.publisher American Society of Parasitologists en_US
dc.relation.ispartofseries Journal of Parasitology, 87(5):1140-1143;
dc.subject ICT Filariasis Card Test en_US
dc.subject Capillary Blood en_US
dc.subject Knott's Concentration en_US
dc.subject Chamber Methods en_US
dc.title Evaluation of ICT Filariasis Card Test Using Whole Capillary Blood: Comparison with Knott's Concentration and Counting Chamber Methods en_US
dc.type Article en_US


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