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The effect of plasmodium falciparum on cognition: A systematic review. Tropical Medicine & International Health

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dc.contributor.author Carte, JA
dc.contributor.author Kihara, Michael
dc.contributor.author Charles, R. J. C. Newton
dc.date.accessioned 2015-10-07T08:09:17Z
dc.date.available 2015-10-07T08:09:17Z
dc.date.issued 2006
dc.identifier.citation Michael Kihara1, Julie A. Carter1,2and Charles R. J. C. Newton1,31 The Centre for Geographical Medicine Research (Coast), KEMRI, Kilifi, Kenya2 Centre for International Child Health, Institute of Child Health, London, UK3 Neurosciences Unit, Institute of Child Health, The Wolfson Centre, London, UK en_US
dc.identifier.uri http://hdl.handle.net/11732/1298
dc.description.abstract objective Systematic review to investigate the relationship between Plasmodium falciparum infectionand cognitive function.method We searched MEDLINE, EMBASE and PsycINFO, and hand-searched journals and PhDtheses. The inclusion criteria were (1) use of standardized tests for the specific populations and/orappropriate controls; (2) clear differentiation between children and adults. Eighteen studies were eli-gible, of which three gave information on all cognitive domains considered in the review.results Deficits in attention, memory, visuo-spatial skills, language and executive functions may occurafter malaria infection. These deficits are not only caused by cerebral falciparum malaria, but alsoappear to occur in less severe infections. P. falciparum seems to affect the brain globally, not in alocalised fashion. Outcome depends on both biological and social risk factors.conclusion Future research should seek to establish the extent of these cognitive deficits using cul-turally appropriate techniques and well-defined criteria of disease en_US
dc.title The effect of plasmodium falciparum on cognition: A systematic review. Tropical Medicine & International Health en_US
dc.type Article en_US


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